Cannabis has been cultivated as a crop for millennia, but there’s been little historical or archeological evidence showing when humans began to use the plant for what it’s best known for today: getting high.
The 1964 discovery and isolation of cannabinoids in marijuana, the therapeutically active components that provide relief for a wide variety of diseases and conditions, has led to research about the endogenous cannabinoid, or endocannabinoid, system in humans.