Some early “Betty Boop” from the Fleischer Brothers, “Small Fry” off “Merry Melodies”, Disney’s “Alice in Wonderland”, Bakshi’s “American Pop” and, of course, “Heavy Metal”.
Check out all of Bakshi’s stuff for more drug references… they are everywhere in his work.
The early cartoons were from “Weird Cartoons, Vol. 2” from Rhino Home Video
The early-cartoon tobacco references connotate “adult behavior”, but the hookah-smoking catterpillar doesn’t seem to mind smoking up little Alice and telling her to eat mushrooms.
As well, Bakshi seemed to accurately display the difference between weed and coke heads. And hey kids, always take it easy on the nyborg … no interstellar impaired driving.