Just days after Colorado became the first US state to allow recreational marijuana use, French researchers have reportedly discovered a way to reduce the negative effects of the marijuana “buzz”.
On Thursday, French scientists said their work had found that a naturally occurring hormone acts as spontaneous defense in the brain against the “high” caused by marijuana.
Studying lab rats, the researchers found that the steroid hormone pregnenolone reduced the activity of a particular brain molecule called the type-1 cannabinoid receptor (CB1).
The hormone, which was not previously believed to have any biological effect of its own, actually cancels out the mild euphoria induced by THC, the psychoactive ingredient in marijuana, according to lead author Pier Vincenzo Piazza of the French Institute of Health and Medical Research (INSERM).
“These researchers weren’t trying to be buzzkills,” said the journal Science, in which the study appears. “Their discovery could lead to new approaches to treating marijuana intoxication and addiction — and it may allow researchers to isolate the medicinal properties of cannabis while blocking its behavioral and somatic effects.”
– Read the entire article at France24.