A team of researchers at the Imperial College of London has found cannabinoid receptors in rat spinal cords which act to modulate pain. Their results were published in the journal Molecular and Cellular Neuroscience.
Researcher Dr Andrew Rice told Reuters “We have achieved a really important step in terms of divorcing the psychoactive side-effects of cannabis from their pain-relieving effects.”
They hope to develop cannabinoid-based synthetic drugs which could be delivered right to the spinal cord. These could be especially effective for “painful neuropathy” against which opiates are ineffective.
* Abstract for article in the Molecular and Cellular Neuroscience Acedemic Press www.idealibrary.com/links/artid/mcne.2000.0844